Folklore Clinical Variant Interpretation MCP
Hosted, read-only MCP server from Helena Bioinformatics for ACMG/AMP germline variant classification, gene-disease evidence and literature.
Tags
Description
Connect to https://api.helena.bio/folklore/v1/mcp over Streamable HTTP; access is anonymous. 11 tools, including classify_germline_variant, resolve_gene, get_gene_profile, get_gene_disease_associations (ClinGen), search_disease_genes, search_variant_literature and search_literature_corpus. Input is one public GRCh38 nuclear germline SNV or simple indel under 50 bp (HGVS, SPDI, rsID or coordinates). Results are typed outcomes (resolved, ambiguous, not_found, unsupported...) with criteria, evidence and provenance. Meant for professional review, not diagnosis, and not for patient data. The public adapter repo is Apache-2.0. Folklore is Helena's commercial clinical genomics product; a live initialize returned server folklore 1.7.0. Submitted via listing request #11 by the operator.
Agent access
Sources
- https://folklore.helena.bio/integrations/mcp
- https://github.com/helena-bioinformatics/folklore-mcp
- https://folklore.helena.bio/llms.txt
- https://www.helena.bio/
Machine-readable
- JSON
- Markdown
- Source file on GitHub (edit via pull request)